G418-0516 Screening compound: 4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzamide

G418-0516 Screening compound: 4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzamide
G418-0516 Screening compound: 4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G418-0516
4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G418-0516

Molecular Formula

C26H24ClN3O2 (C26 H24 ClN3 O2)

Compound Name

4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]benzamide

IUPAC name

4-tert-butyl-N-[(2-chlorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]benzamide

SMILES

CC(C)(C)c(cc1)ccc1C(NC(c1nnc(-c2ccccc2)o1)c(cccc1)c1Cl)=O

InChI

InChI=1S/C26H24ClN3O2/c1-26(2,3)19-15-13-17(14-16-19)23(31)28-22(20-11-7-8-12-21(20)27)25-30-29-24(32-25)18-9-5-4-6-10-18/h4-16,22H,1-3H3,(H,28,31)/t22-/m1/s1

InChI Key

ILHZEJYVIMDQDX-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD09662152

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.95

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.461

Distribution Coefficient, logD

6.458

Water Solubility, LogSw

-6.15

Polar Surface Area

54.248

Acid Dissociation Constant (pKa)

9.55

Base Dissociation Constant (pKb)

-5.89

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.20

G418-0516 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Antiviral Library (67538 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G418-0516 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G418-0516?
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What is the minimum amount of G418-0516 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G418-0516
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G418-0516
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G418-0516 available by request