G418-0728 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea

G418-0728 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea
G418-0728 Screening compound: 1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G418-0728
1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G418-0728

Molecular Formula

C23H18ClFN4O2 (C23 H18 ClFN4 O2)

Compound Name

1-{[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea

IUPAC name

1-{[5-(2-chlorophenyl)-134-oxadiazol-2-yl](phenyl)methyl}-3-(3-fluoro-4-methylphenyl)urea

SMILES

Cc(ccc(NC(NC(c1nnc(-c(cccc2)c2Cl)o1)c1ccccc1)=O)c1)c1F

InChI

InChI=1S/C23H18ClFN4O2/c1-14-11-12-16(13-19(14)25)26-23(30)27-20(15-7-3-2-4-8-15)22-29-28-21(31-22)17-9-5-6-10-18(17)24/h2-13,20H,1H3,(H2,26,27,30)/t20-/m1/s1

InChI Key

XAAOOKAGQFMRPF-HXUWFJFHSA-N

MDL Number (MFCD)

MFCD12129767

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

436.87

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.265

Distribution Coefficient, logD

5.265

Water Solubility, LogSw

-5.62

Polar Surface Area

63.460

Acid Dissociation Constant (pKa)

11.13

Base Dissociation Constant (pKb)

0.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

G418-0728 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Immunological Library (6760 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G418-0728 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G418-0728?
Check Price and Availability of G418-0728, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G418-0728 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G418-0728
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G418-0728
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G418-0728 available by request