G418-1111 Screening compound: N-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide

G418-1111 Screening compound: N-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide
G418-1111 Screening compound: N-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G418-1111
N-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G418-1111

Molecular Formula

C24H20FN3O3 (C24 H20 FN3 O3)

Compound Name

N-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide

IUPAC name

N-[(4-fluorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]-2-(3-methoxyphenyl)acetamide

SMILES

COc1cccc(CC(NC(c2nnc(-c3ccccc3)o2)c(cc2)ccc2F)=O)c1

InChI

InChI=1S/C24H20FN3O3/c1-30-20-9-5-6-16(14-20)15-21(29)26-22(17-10-12-19(25)13-11-17)24-28-27-23(31-24)18-7-3-2-4-8-18/h2-14,22H,15H2,1H3,(H,26,29)/t22-/m1/s1

InChI Key

FSJYIOGNWLQWCL-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD15011787

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.891

Distribution Coefficient, logD

3.891

Water Solubility, LogSw

-4.15

Polar Surface Area

61.578

Acid Dissociation Constant (pKa)

10.12

Base Dissociation Constant (pKb)

-4.96

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

12.50

G418-1111 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G418-1111 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G418-1111?
Check Price and Availability of G418-1111, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G418-1111 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G418-1111
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G418-1111
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G418-1111 available by request