G418-1128 Screening compound: 1-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea

G418-1128 Screening compound: 1-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea
G418-1128 Screening compound: 1-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G418-1128
1-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G418-1128

Molecular Formula

C23H16F4N4O2 (C23 H16 F4 N4 O2)

Compound Name

1-[(4-fluorophenyl)(5-phenyl-1,3,4-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea

IUPAC name

1-[(4-fluorophenyl)(5-phenyl-134-oxadiazol-2-yl)methyl]-3-[2-(trifluoromethyl)phenyl]urea

SMILES

O=C(NC(c1nnc(-c2ccccc2)o1)c(cc1)ccc1F)Nc1c(C(F)(F)F)cccc1

InChI

InChI=1S/C23H16F4N4O2/c24-16-12-10-14(11-13-16)19(21-31-30-20(33-21)15-6-2-1-3-7-15)29-22(32)28-18-9-5-4-8-17(18)23(25,26)27/h1-13,19H,(H2,28,29,32)/t19-/m1/s1

InChI Key

YXXAQLGRXFNOII-LJQANCHMSA-N

MDL Number (MFCD)

MFCD15011789

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.4

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.735

Distribution Coefficient, logD

4.734

Water Solubility, LogSw

-4.82

Polar Surface Area

62.762

Acid Dissociation Constant (pKa)

11.11

Base Dissociation Constant (pKb)

-0.92

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

G418-1128 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G418-1128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G418-1128?
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What is the minimum amount of G418-1128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G418-1128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G418-1128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G418-1128 available by request