G419-0366 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamide

G419-0366 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamide
G419-0366 Screening compound: N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G419-0366
N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G419-0366

Molecular Formula

C23H18ClF3N4O3 (C23 H18 ClF3 N4 O3)

Compound Name

N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-a]pyrazin-5-yl]acetamide

IUPAC name

N-[2-chloro-5-(trifluoromethyl)phenyl]-2-[2-(4-ethoxyphenyl)-4-oxo-4H5H-pyrazolo[15-a]pyrazin-5-yl]acetamide

SMILES

CCOc(cc1)ccc1-c1nn(C=CN(CC(Nc(cc(C(F)(F)F)cc2)c2Cl)=O)C2=O)c2c1

InChI

InChI=1S/C23H18ClF3N4O3/c1-2-34-16-6-3-14(4-7-16)18-12-20-22(33)30(9-10-31(20)29-18)13-21(32)28-19-11-15(23(25,26)27)5-8-17(19)24/h3-12H,2,13H2,1H3,(H,28,32)

InChI Key

GKBYHLPKDDEXSD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140377

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.87

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.134

Distribution Coefficient, logD

4.103

Water Solubility, LogSw

-4.43

Polar Surface Area

57.546

Acid Dissociation Constant (pKa)

8.53

Base Dissociation Constant (pKb)

-1.10

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

G419-0366 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with G419-0366 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G419-0366?
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What is the minimum amount of G419-0366 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G419-0366
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G419-0366
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G419-0366 available by request