G420-0450 Screening compound: N-(3,5-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

G420-0450 Screening compound: N-(3,5-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide
G420-0450 Screening compound: N-(3,5-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G420-0450
N-(3,5-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G420-0450

Molecular Formula

C26H22N4O3S (C26 H22 N4 O3 S)

Compound Name

N-(3,5-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

IUPAC name

N-(35-dimethoxyphenyl)-2-{[2-(naphthalen-1-yl)pyrazolo[15-a]pyrazin-4-yl]sulfanyl}acetamide

SMILES

COc1cc(NC(CSc(c2c3)nccn2nc3-c2cccc3ccccc23)=O)cc(OC)c1

InChI

InChI=1S/C26H22N4O3S/c1-32-19-12-18(13-20(14-19)33-2)28-25(31)16-34-26-24-15-23(29-30(24)11-10-27-26)22-9-5-7-17-6-3-4-8-21(17)22/h3-15H,16H2,1-2H3,(H,28,31)

InChI Key

AZUGWCJEFSXKQN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11995292

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.55

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.690

Distribution Coefficient, logD

4.689

Water Solubility, LogSw

-4.93

Polar Surface Area

57.714

Acid Dissociation Constant (pKa)

10.79

Base Dissociation Constant (pKb)

4.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.50

G420-0450 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G420-0450 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G420-0450?
Check Price and Availability of G420-0450, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G420-0450 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G420-0450
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G420-0450
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G420-0450 available by request