G420-0451 Screening compound: N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

G420-0451 Screening compound: N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide
G420-0451 Screening compound: N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G420-0451
N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G420-0451

Molecular Formula

C25H20N4OS2 (C25 H20 N4 OS2)

Compound Name

N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[1,5-a]pyrazin-4-yl]sulfanyl}acetamide

IUPAC name

N-[3-(methylsulfanyl)phenyl]-2-{[2-(naphthalen-1-yl)pyrazolo[15-a]pyrazin-4-yl]sulfanyl}acetamide

SMILES

CSc1cccc(NC(CSc(c2c3)nccn2nc3-c2cccc3ccccc23)=O)c1

InChI

InChI=1S/C25H20N4OS2/c1-31-19-9-5-8-18(14-19)27-24(30)16-32-25-23-15-22(28-29(23)13-12-26-25)21-11-4-7-17-6-2-3-10-20(17)21/h2-15H,16H2,1H3,(H,27,30)

InChI Key

JTPFYXYSLFCYOS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11995293

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.012

Distribution Coefficient, logD

5.012

Water Solubility, LogSw

-5.20

Polar Surface Area

42.627

Acid Dissociation Constant (pKa)

12.56

Base Dissociation Constant (pKb)

4.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.00

G420-0451 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G420-0451 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G420-0451?
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What is the minimum amount of G420-0451 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G420-0451
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G420-0451
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G420-0451 available by request