G421-0120 Screening compound: N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

G421-0120 Screening compound: N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine
G421-0120 Screening compound: N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0120
N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0120

Molecular Formula

C22H24N4O (C22 H24 N4 O)

Compound Name

N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

IUPAC name

N-(4-methoxyphenyl)-6-[(4-methylphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-amine

SMILES

Cc1ccc(CN(CC2)Cc3c2nc(Nc(cc2)ccc2OC)nc3)cc1

InChI

InChI=1S/C22H24N4O/c1-16-3-5-17(6-4-16)14-26-12-11-21-18(15-26)13-23-22(25-21)24-19-7-9-20(27-2)10-8-19/h3-10,13H,11-12,14-15H2,1-2H3,(H,23,24,25)

InChI Key

VIXVGDGBPBVFGV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15011927

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

360.46

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.156

Distribution Coefficient, logD

4.110

Water Solubility, LogSw

-4.01

Polar Surface Area

41.817

Acid Dissociation Constant (pKa)

17.98

Base Dissociation Constant (pKb)

6.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

G421-0120 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with G421-0120 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0120?
Check Price and Availability of G421-0120, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0120 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0120
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0120
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0120 available by request