G421-0166 Screening compound: N-(2,4-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

G421-0166 Screening compound: N-(2,4-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine
G421-0166 Screening compound: N-(2,4-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0166
N-(2,4-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0166

Molecular Formula

C20H17F3N4 (C20 H17 F3 N4)

Compound Name

N-(2,4-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

IUPAC name

N-(24-difluorophenyl)-6-[(2-fluorophenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-amine

SMILES

Fc(cc1)cc(F)c1Nc1nc(CCN(Cc(cccc2)c2F)C2)c2cn1

InChI

InChI=1S/C20H17F3N4/c21-15-5-6-19(17(23)9-15)26-20-24-10-14-12-27(8-7-18(14)25-20)11-13-3-1-2-4-16(13)22/h1-6,9-10H,7-8,11-12H2,(H,24,25,26)

InChI Key

BZRSICYICAQNKF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15011956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.38

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.190

Distribution Coefficient, logD

4.185

Water Solubility, LogSw

-4.15

Polar Surface Area

33.575

Acid Dissociation Constant (pKa)

14.63

Base Dissociation Constant (pKb)

5.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G421-0166 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Agro:
  • Agro

References: we are preparing a list of scientific research reports with G421-0166 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0166?
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What is the minimum amount of G421-0166 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0166
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0166
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0166 available by request