G421-0296 Screening compound: 6-[(4-chloro-3-fluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

G421-0296 Screening compound: 6-[(4-chloro-3-fluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine
G421-0296 Screening compound: 6-[(4-chloro-3-fluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0296
6-[(4-chloro-3-fluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0296

Molecular Formula

C22H22ClFN4O2 (C22 H22 ClFN4 O2)

Compound Name

6-[(4-chloro-3-fluorophenyl)methyl]-N-(3,5-dimethoxyphenyl)-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

IUPAC name

6-[(4-chloro-3-fluorophenyl)methyl]-N-(35-dimethoxyphenyl)-5H6H7H8H-pyrido[43-d]pyrimidin-2-amine

SMILES

COc1cc(Nc2nc(CCN(Cc(cc3)cc(F)c3Cl)C3)c3cn2)cc(OC)c1

InChI

InChI=1S/C22H22ClFN4O2/c1-29-17-8-16(9-18(10-17)30-2)26-22-25-11-15-13-28(6-5-21(15)27-22)12-14-3-4-19(23)20(24)7-14/h3-4,7-11H,5-6,12-13H2,1-2H3,(H,25,26,27)

InChI Key

NBRFBQMQLSBPNT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012052

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.465

Distribution Coefficient, logD

4.463

Water Solubility, LogSw

-4.47

Polar Surface Area

49.361

Acid Dissociation Constant (pKa)

16.35

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

References: we are preparing a list of scientific research reports with G421-0296 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0296?
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What is the minimum amount of G421-0296 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0296
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0296
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0296 available by request