G421-0304 Screening compound: N-(3,5-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

G421-0304 Screening compound: N-(3,5-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine
G421-0304 Screening compound: N-(3,5-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0304
N-(3,5-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0304

Molecular Formula

C26H32N4O4 (C26 H32 N4 O4)

Compound Name

N-(3,5-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-amine

IUPAC name

N-(35-dimethoxyphenyl)-6-{[3-methoxy-4-(propan-2-yloxy)phenyl]methyl}-5H6H7H8H-pyrido[43-d]pyrimidin-2-amine

SMILES

CC(C)Oc(ccc(CN(CC1)Cc2c1nc(Nc1cc(OC)cc(OC)c1)nc2)c1)c1OC

InChI

InChI=1S/C26H32N4O4/c1-17(2)34-24-7-6-18(10-25(24)33-5)15-30-9-8-23-19(16-30)14-27-26(29-23)28-20-11-21(31-3)13-22(12-20)32-4/h6-7,10-14,17H,8-9,15-16H2,1-5H3,(H,27,28,29)

InChI Key

XXKFYXZWPCTTNQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012057

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

464.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.179

Distribution Coefficient, logD

4.006

Water Solubility, LogSw

-4.12

Polar Surface Area

63.880

Acid Dissociation Constant (pKa)

16.35

Base Dissociation Constant (pKb)

7.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G421-0304 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with G421-0304 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0304?
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What is the minimum amount of G421-0304 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0304
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0304
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0304 available by request