G421-0341 Screening compound: N-(2-FLUOROPHENYL)-N-[6-(2,3,4-TRIMETHOXYBENZYL)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-YL]AMINE

G421-0341 Screening compound: N-(2-FLUOROPHENYL)-N-[6-(2,3,4-TRIMETHOXYBENZYL)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-YL]AMINE
G421-0341 Screening compound: N-(2-FLUOROPHENYL)-N-[6-(2,3,4-TRIMETHOXYBENZYL)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-YL]AMINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0341
N-(2-FLUOROPHENYL)-N-[6-(2,3,4-TRIMETHOXYBENZYL)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-YL]AMINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0341

Molecular Formula

C23H25FN4O3 (C23 H25 FN4 O3)

Compound Name

N-(2-FLUOROPHENYL)-N-[6-(2,3,4-TRIMETHOXYBENZYL)-5,6,7,8-TETRAHYDROPYRIDO[4,3-D]PYRIMIDIN-2-YL]AMINE

IUPAC name

n/a

SMILES

COc(ccc(CN(CC1)Cc2c1nc(Nc(cccc1)c1F)nc2)c1OC)c1OC

InChI

InChI=1S/C23H25FN4O3/c1-29-20-9-8-15(21(30-2)22(20)31-3)13-28-11-10-18-16(14-28)12-25-23(26-18)27-19-7-5-4-6-17(19)24/h4-9,12H,10-11,13-14H2,1-3H3,(H,25,26,27)

InChI Key

DFCRXGQCRIHMCZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012081

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.48

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.708

Distribution Coefficient, logD

3.527

Water Solubility, LogSw

-3.82

Polar Surface Area

56.640

Acid Dissociation Constant (pKa)

16.42

Base Dissociation Constant (pKb)

7.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

G421-0341 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-0341 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0341?
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What is the minimum amount of G421-0341 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0341
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0341
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0341 available by request