G421-0632 Screening compound: 4-{6-[(2,5-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

G421-0632 Screening compound: 4-{6-[(2,5-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine
G421-0632 Screening compound: 4-{6-[(2,5-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0632
4-{6-[(2,5-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0632

Molecular Formula

C20H26N4O3 (C20 H26 N4 O3)

Compound Name

4-{6-[(2,5-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

IUPAC name

4-{6-[(25-dimethoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}morpholine

SMILES

COc(cc1)cc(CN(CC2)Cc3c2nc(N2CCOCC2)nc3)c1OC

InChI

InChI=1S/C20H26N4O3/c1-25-17-3-4-19(26-2)15(11-17)13-23-6-5-18-16(14-23)12-21-20(22-18)24-7-9-27-10-8-24/h3-4,11-12H,5-10,13-14H2,1-2H3

InChI Key

SLCQQPCAXLROFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012301

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

370.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.013

Distribution Coefficient, logD

1.724

Water Solubility, LogSw

-2.30

Polar Surface Area

49.689

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G421-0632 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

PI3K-Targeted Library (17255 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-0632 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0632?
Check Price and Availability of G421-0632, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0632 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0632
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0632
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0632 available by request