G421-0643 Screening compound: 4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

G421-0643 Screening compound: 4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine
G421-0643 Screening compound: 4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0643
4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0643

Molecular Formula

C19H24N4O2 (C19 H24 N4 O2)

Compound Name

4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

IUPAC name

4-{6-[(2-methoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}morpholine

SMILES

COc1c(CN(CC2)Cc3c2nc(N2CCOCC2)nc3)cccc1

InChI

InChI=1S/C19H24N4O2/c1-24-18-5-3-2-4-15(18)13-22-7-6-17-16(14-22)12-20-19(21-17)23-8-10-25-11-9-23/h2-5,12H,6-11,13-14H2,1H3

InChI Key

GUSILPXHSQZYQB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012310

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

340.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.034

Distribution Coefficient, logD

2.019

Water Solubility, LogSw

-1.98

Polar Surface Area

42.145

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.40

G421-0643 in Drug Discovery

Included in Screening Libraries

CNS BBB Library (22607 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-0643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0643?
Check Price and Availability of G421-0643, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0643 available by request