G421-0646 Screening compound: 4-{6-[(2-chlorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

G421-0646 Screening compound: 4-{6-[(2-chlorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine
G421-0646 Screening compound: 4-{6-[(2-chlorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0646
4-{6-[(2-chlorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0646

Molecular Formula

C18H21ClN4O (C18 H21 ClN4 O)

Compound Name

4-{6-[(2-chlorophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}morpholine

IUPAC name

4-{6-[(2-chlorophenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}morpholine

SMILES

Clc1c(CN(CC2)Cc3c2nc(N2CCOCC2)nc3)cccc1

InChI

InChI=1S/C18H21ClN4O/c19-16-4-2-1-3-14(16)12-22-6-5-17-15(13-22)11-20-18(21-17)23-7-9-24-10-8-23/h1-4,11H,5-10,12-13H2

InChI Key

FWORRDMWMCJUAQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012313

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.84

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.566

Distribution Coefficient, logD

2.562

Water Solubility, LogSw

-2.95

Polar Surface Area

34.515

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.44

G421-0646 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G421-0646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0646?
Check Price and Availability of G421-0646, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0646 available by request