G421-0682 Screening compound: 1-{6-[(2,3-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}PYRROLIDINE

G421-0682 Screening compound: 1-{6-[(2,3-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}PYRROLIDINE
G421-0682 Screening compound: 1-{6-[(2,3-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}PYRROLIDINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0682
1-{6-[(2,3-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}PYRROLIDINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0682

Molecular Formula

C20H26N4O2 (C20 H26 N4 O2)

Compound Name

1-{6-[(2,3-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}PYRROLIDINE

IUPAC name

n/a

SMILES

COc(cccc1CN(CC2)Cc3c2nc(N2CCCC2)nc3)c1OC

InChI

InChI=1S/C20H26N4O2/c1-25-18-7-5-6-15(19(18)26-2)13-23-11-8-17-16(14-23)12-21-20(22-17)24-9-3-4-10-24/h5-7,12H,3-4,8-11,13-14H2,1-2H3

InChI Key

ZJSHTVPCOSYRQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012342

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

354.45

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.780

Distribution Coefficient, logD

2.491

Water Solubility, LogSw

-2.79

Polar Surface Area

42.319

Acid Dissociation Constant (pKa)

19.71

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G421-0682 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-0682 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0682?
Check Price and Availability of G421-0682, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0682 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0682
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0682
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0682 available by request