G421-0878 Screening compound: 4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}methyl)-N,N-dimethylaniline

G421-0878 Screening compound: 4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}methyl)-N,N-dimethylaniline
G421-0878 Screening compound: 4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}methyl)-N,N-dimethylaniline alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0878
4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}methyl)-N,N-dimethylaniline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0878

Molecular Formula

C27H34N6O (C27 H34 N6 O)

Compound Name

4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-6-yl}methyl)-N,N-dimethylaniline

IUPAC name

4-({2-[4-(4-methoxyphenyl)piperazin-1-yl]-5H6H7H8H-pyrido[43-d]pyrimidin-6-yl}methyl)-NN-dimethylaniline

SMILES

CN(C)c1ccc(CN(CC2)Cc3c2nc(N(CC2)CCN2c(cc2)ccc2OC)nc3)cc1

InChI

InChI=1S/C27H34N6O/c1-30(2)23-6-4-21(5-7-23)19-31-13-12-26-22(20-31)18-28-27(29-26)33-16-14-32(15-17-33)24-8-10-25(34-3)11-9-24/h4-11,18H,12-17,19-20H2,1-3H3

InChI Key

PEUREPJEUXOJMY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012453

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.61

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.916

Distribution Coefficient, logD

3.904

Water Solubility, LogSw

-3.93

Polar Surface Area

40.215

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

G421-0878 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G421-0878 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0878?
Check Price and Availability of G421-0878, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0878 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0878
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0878
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0878 available by request