G421-0983 Screening compound: 1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-phenylpiperazine

G421-0983 Screening compound: 1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-phenylpiperazine
G421-0983 Screening compound: 1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-phenylpiperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0983
1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-phenylpiperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0983

Molecular Formula

C27H33N5O2 (C27 H33 N5 O2)

Compound Name

1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-phenylpiperazine

IUPAC name

1-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}-4-phenylpiperazine

SMILES

CCOc(ccc(CN(CC1)Cc2c1nc(N(CC1)CCN1c1ccccc1)nc2)c1)c1OC

InChI

InChI=1S/C27H33N5O2/c1-3-34-25-10-9-21(17-26(25)33-2)19-30-12-11-24-22(20-30)18-28-27(29-24)32-15-13-31(14-16-32)23-7-5-4-6-8-23/h4-10,17-18H,3,11-16,19-20H2,1-2H3

InChI Key

GJDODBMZMQGRRH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012534

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

459.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.640

Distribution Coefficient, logD

3.467

Water Solubility, LogSw

-3.65

Polar Surface Area

44.707

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

7.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

G421-0983 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G421-0983 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0983?
Check Price and Availability of G421-0983, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0983 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0983
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0983
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0983 available by request