G421-0993 Screening compound: 1-{6-[(2-METHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-PHENYLPIPERAZINE

G421-0993 Screening compound: 1-{6-[(2-METHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-PHENYLPIPERAZINE
G421-0993 Screening compound: 1-{6-[(2-METHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-PHENYLPIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-0993
1-{6-[(2-METHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-PHENYLPIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-0993

Molecular Formula

C25H29N5O (C25 H29 N5 O)

Compound Name

1-{6-[(2-METHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-PHENYLPIPERAZINE

IUPAC name

1-{6-[(2-methoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}-4-phenylpiperazine

SMILES

COc1c(CN(CC2)Cc3c2nc(N(CC2)CCN2c2ccccc2)nc3)cccc1

InChI

InChI=1S/C25H29N5O/c1-31-24-10-6-5-7-20(24)18-28-12-11-23-21(19-28)17-26-25(27-23)30-15-13-29(14-16-30)22-8-3-2-4-9-22/h2-10,17H,11-16,18-19H2,1H3

InChI Key

ASKCMFQETRZKNW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012541

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.54

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.828

Distribution Coefficient, logD

3.813

Water Solubility, LogSw

-3.88

Polar Surface Area

37.497

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

G421-0993 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-0993 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-0993?
Check Price and Availability of G421-0993, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-0993 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-0993
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-0993
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-0993 available by request