G421-1086 Screening compound: 1-{6-[(2,5-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-(2-METHOXYPHENYL)PIPERAZINE

G421-1086 Screening compound: 1-{6-[(2,5-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-(2-METHOXYPHENYL)PIPERAZINE
G421-1086 Screening compound: 1-{6-[(2,5-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-(2-METHOXYPHENYL)PIPERAZINE alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-1086
1-{6-[(2,5-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-(2-METHOXYPHENYL)PIPERAZINE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-1086

Molecular Formula

C27H33N5O3 (C27 H33 N5 O3)

Compound Name

1-{6-[(2,5-DIMETHOXYPHENYL)METHYL]-5H,6H,7H,8H-PYRIDO[4,3-D]PYRIMIDIN-2-YL}-4-(2-METHOXYPHENYL)PIPERAZINE

IUPAC name

1-{6-[(25-dimethoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}-4-(2-methoxyphenyl)piperazine

SMILES

COc(cc1)cc(CN(CC2)Cc3c2nc(N(CC2)CCN2c(cccc2)c2OC)nc3)c1OC

InChI

InChI=1S/C27H33N5O3/c1-33-22-8-9-25(34-2)20(16-22)18-30-11-10-23-21(19-30)17-28-27(29-23)32-14-12-31(13-15-32)24-6-4-5-7-26(24)35-3/h4-9,16-17H,10-15,18-19H2,1-3H3

InChI Key

JXKOTQOYBLZNQV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012610

Chemical and Physical Properties

Saltdata

HCl

Molecular Weight

475.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.807

Distribution Coefficient, logD

3.519

Water Solubility, LogSw

-3.89

Polar Surface Area

52.370

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

7.37

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

G421-1086 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with G421-1086 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-1086?
Check Price and Availability of G421-1086, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-1086 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-1086
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-1086
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-1086 available by request