G421-1096 Screening compound: 1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazine

G421-1096 Screening compound: 1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazine
G421-1096 Screening compound: 1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-1096
1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-1096

Molecular Formula

C26H31N5O2 (C26 H31 N5 O2)

Compound Name

1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazine

IUPAC name

1-(2-methoxyphenyl)-4-{6-[(2-methoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}piperazine

SMILES

COc1c(CN(CC2)Cc3c2nc(N(CC2)CCN2c(cccc2)c2OC)nc3)cccc1

InChI

InChI=1S/C26H31N5O2/c1-32-24-9-5-3-7-20(24)18-29-12-11-22-21(19-29)17-27-26(28-22)31-15-13-30(14-16-31)23-8-4-6-10-25(23)33-2/h3-10,17H,11-16,18-19H2,1-2H3

InChI Key

WTBZEWPGUVCSEQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012618

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.829

Distribution Coefficient, logD

3.814

Water Solubility, LogSw

-3.92

Polar Surface Area

44.826

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G421-1096 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G421-1096 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-1096?
Check Price and Availability of G421-1096, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-1096 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-1096
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-1096
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-1096 available by request