G421-1126 Screening compound: 1-{6-[(3-bromophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine

G421-1126 Screening compound: 1-{6-[(3-bromophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine
G421-1126 Screening compound: 1-{6-[(3-bromophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-1126
1-{6-[(3-bromophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-1126

Molecular Formula

C23H25BrN6 (C23 H25 BrN6)

Compound Name

1-{6-[(3-bromophenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{6-[(3-bromophenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}-4-(pyridin-2-yl)piperazine

SMILES

Brc1cc(CN(CC2)Cc3c2nc(N(CC2)CCN2c2ncccc2)nc3)ccc1

InChI

InChI=1S/C23H25BrN6/c24-20-5-3-4-18(14-20)16-28-9-7-21-19(17-28)15-26-23(27-21)30-12-10-29(11-13-30)22-6-1-2-8-25-22/h1-6,8,14-15H,7,9-13,16-17H2

InChI Key

SXDTWBSTFFNDAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012622

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

465.4

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.100

Distribution Coefficient, logD

4.087

Water Solubility, LogSw

-4.23

Polar Surface Area

38.378

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

G421-1126 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G421-1126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-1126?
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What is the minimum amount of G421-1126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-1126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-1126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-1126 available by request