G421-1236 Screening compound: 2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine

G421-1236 Screening compound: 2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine
G421-1236 Screening compound: 2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-1236
2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-1236

Molecular Formula

C25H31N7O2 (C25 H31 N7 O2)

Compound Name

2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine

IUPAC name

2-(4-{6-[(4-ethoxy-3-methoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}piperazin-1-yl)pyrimidine

SMILES

CCOc(ccc(CN(CC1)Cc2c1nc(N(CC1)CCN1c1ncccn1)nc2)c1)c1OC

InChI

InChI=1S/C25H31N7O2/c1-3-34-22-6-5-19(15-23(22)33-2)17-30-10-7-21-20(18-30)16-28-25(29-21)32-13-11-31(12-14-32)24-26-8-4-9-27-24/h4-6,8-9,15-16H,3,7,10-14,17-18H2,1-2H3

InChI Key

GFGAHUNQYSTYNL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012687

Chemical and Physical Properties

Saltdata

2HCl

Molecular Weight

461.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.805

Distribution Coefficient, logD

2.632

Water Solubility, LogSw

-2.83

Polar Surface Area

63.069

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

7.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

G421-1236 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G421-1236 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-1236?
Check Price and Availability of G421-1236, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G421-1236 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-1236
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-1236
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-1236 available by request