G421-1286 Screening compound: 1-{6-[(2,4-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine

G421-1286 Screening compound: 1-{6-[(2,4-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine
G421-1286 Screening compound: 1-{6-[(2,4-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound G421-1286
1-{6-[(2,4-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G421-1286

Molecular Formula

C26H30FN5O2 (C26 H30 FN5 O2)

Compound Name

1-{6-[(2,4-dimethoxyphenyl)methyl]-5H,6H,7H,8H-pyrido[4,3-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine

IUPAC name

1-{6-[(24-dimethoxyphenyl)methyl]-5H6H7H8H-pyrido[43-d]pyrimidin-2-yl}-4-(2-fluorophenyl)piperazine

SMILES

COc1cc(OC)c(CN(CC2)Cc3c2nc(N(CC2)CCN2c(cccc2)c2F)nc3)cc1

InChI

InChI=1S/C26H30FN5O2/c1-33-21-8-7-19(25(15-21)34-2)17-30-10-9-23-20(18-30)16-28-26(29-23)32-13-11-31(12-14-32)24-6-4-3-5-22(24)27/h3-8,15-16H,9-14,17-18H2,1-2H3

InChI Key

URCLBVFBAQYJMZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012712

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.56

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.005

Distribution Coefficient, logD

3.997

Water Solubility, LogSw

-4.12

Polar Surface Area

44.740

Acid Dissociation Constant (pKa)

20.66

Base Dissociation Constant (pKb)

5.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

G421-1286 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G421-1286 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G421-1286?
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What is the minimum amount of G421-1286 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G421-1286
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G421-1286
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G421-1286 available by request