G423-0027 Screening compound: N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]butanamide

G423-0027 Screening compound: N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]butanamide
G423-0027 Screening compound: N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0027
N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0027

Molecular Formula

C22H19ClFN5O2 (C22 H19 ClFN5 O2)

Compound Name

N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]butanamide

IUPAC name

N-[(4-chlorophenyl)methyl]-4-[7-(3-fluorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]butanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c1cc(F)ccc1)C2=O)NCc(cc1)ccc1Cl

InChI

InChI=1S/C22H19ClFN5O2/c23-16-9-7-15(8-10-16)14-25-20(30)6-2-5-19-26-27-21-22(31)28(11-12-29(19)21)18-4-1-3-17(24)13-18/h1,3-4,7-13H,2,5-6,14H2,(H,25,30)

InChI Key

ZNTOBZXQQNGXDN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012771

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.88

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.594

Distribution Coefficient, logD

1.594

Water Solubility, LogSw

-2.64

Polar Surface Area

63.568

Acid Dissociation Constant (pKa)

12.59

Base Dissociation Constant (pKb)

0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

G423-0027 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G423-0027 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0027?
Check Price and Availability of G423-0027, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G423-0027 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0027
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0027
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0027 available by request