G423-0029 Screening compound: 4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

G423-0029 Screening compound: 4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide
G423-0029 Screening compound: 4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0029
4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0029

Molecular Formula

C25H23FN6O2 (C25 H23 FN6 O2)

Compound Name

4-[7-(3-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

IUPAC name

4-[7-(3-fluorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c1cccc(F)c1)C2=O)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C25H23FN6O2/c26-18-5-3-6-19(15-18)31-13-14-32-22(29-30-24(32)25(31)34)9-4-10-23(33)27-12-11-17-16-28-21-8-2-1-7-20(17)21/h1-3,5-8,13-16,28H,4,9-12H2,(H,27,33)

InChI Key

HSEPUSLYAYKTCP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012773

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.125

Distribution Coefficient, logD

1.125

Water Solubility, LogSw

-2.13

Polar Surface Area

73.280

Acid Dissociation Constant (pKa)

14.32

Base Dissociation Constant (pKb)

0.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G423-0029 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G423-0029 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0029?
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What is the minimum amount of G423-0029 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0029
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0029
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0029 available by request