G423-0088 Screening compound: 4-[7-(4-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

G423-0088 Screening compound: 4-[7-(4-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide
G423-0088 Screening compound: 4-[7-(4-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0088
4-[7-(4-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0088

Molecular Formula

C25H23FN6O2 (C25 H23 FN6 O2)

Compound Name

4-[7-(4-fluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

IUPAC name

4-[7-(4-fluorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]-N-[2-(1H-indol-3-yl)ethyl]butanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)ccc1F)C2=O)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C25H23FN6O2/c26-18-8-10-19(11-9-18)31-14-15-32-22(29-30-24(32)25(31)34)6-3-7-23(33)27-13-12-17-16-28-21-5-2-1-4-20(17)21/h1-2,4-5,8-11,14-16,28H,3,6-7,12-13H2,(H,27,33)

InChI Key

WUOBPHOBJXMLRC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140461

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.064

Distribution Coefficient, logD

1.064

Water Solubility, LogSw

-2.02

Polar Surface Area

73.280

Acid Dissociation Constant (pKa)

14.32

Base Dissociation Constant (pKb)

-6.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

G423-0088 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with G423-0088 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0088?
Check Price and Availability of G423-0088, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G423-0088 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0088
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0088
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0088 available by request