G423-0144 Screening compound: 7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

G423-0144 Screening compound: 7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one
G423-0144 Screening compound: 7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0144
7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0144

Molecular Formula

C25H24ClFN6O2 (C25 H24 ClFN6 O2)

Compound Name

7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-8-one

IUPAC name

7-(4-chlorophenyl)-3-{4-[4-(4-fluorophenyl)piperazin-1-yl]-4-oxobutyl}-7H8H-[124]triazolo[43-a]pyrazin-8-one

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)ccc1Cl)C2=O)N(CC1)CCN1c(cc1)ccc1F

InChI

InChI=1S/C25H24ClFN6O2/c26-18-4-8-21(9-5-18)32-16-17-33-22(28-29-24(33)25(32)35)2-1-3-23(34)31-14-12-30(13-15-31)20-10-6-19(27)7-11-20/h4-11,16-17H,1-3,12-15H2

InChI Key

ZHWOZALZFFXMQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08141484

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.96

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.995

Distribution Coefficient, logD

1.995

Water Solubility, LogSw

-2.61

Polar Surface Area

58.749

Acid Dissociation Constant (pKa)

23.66

Base Dissociation Constant (pKb)

5.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G423-0144 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G423-0144 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0144?
Check Price and Availability of G423-0144, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G423-0144 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0144
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0144
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0144 available by request