G423-0156 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide

G423-0156 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide
G423-0156 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0156
4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0156

Molecular Formula

C21H25ClN6O2 (C21 H25 ClN6 O2)

Compound Name

4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide

IUPAC name

4-[7-(4-chlorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]-N-[2-(pyrrolidin-1-yl)ethyl]butanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)ccc1Cl)C2=O)NCCN1CCCC1

InChI

InChI=1S/C21H25ClN6O2/c22-16-6-8-17(9-7-16)27-14-15-28-18(24-25-20(28)21(27)30)4-3-5-19(29)23-10-13-26-11-1-2-12-26/h6-9,14-15H,1-5,10-13H2,(H,23,29)

InChI Key

LSQRMCYRKJWDMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08141492

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

428.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.160

Distribution Coefficient, logD

-1.996

Water Solubility, LogSw

-2.22

Polar Surface Area

67.758

Acid Dissociation Constant (pKa)

13.80

Base Dissociation Constant (pKb)

9.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

G423-0156 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G423-0156 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0156?
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What is the minimum amount of G423-0156 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0156
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0156
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0156 available by request