G423-0158 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-cyclopropylbutanamide

G423-0158 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-cyclopropylbutanamide
G423-0158 Screening compound: 4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-cyclopropylbutanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0158
4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-cyclopropylbutanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0158

Molecular Formula

C18H18ClN5O2 (C18 H18 ClN5 O2)

Compound Name

4-[7-(4-chlorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-cyclopropylbutanamide

IUPAC name

4-[7-(4-chlorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]-N-cyclopropylbutanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)ccc1Cl)C2=O)NC1CC1

InChI

InChI=1S/C18H18ClN5O2/c19-12-4-8-14(9-5-12)23-10-11-24-15(21-22-17(24)18(23)26)2-1-3-16(25)20-13-6-7-13/h4-5,8-11,13H,1-3,6-7H2,(H,20,25)

InChI Key

CWVVJEBBOXFIAM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15012813

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

371.83

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

0.519

Distribution Coefficient, logD

0.519

Water Solubility, LogSw

-2.30

Polar Surface Area

63.624

Acid Dissociation Constant (pKa)

13.65

Base Dissociation Constant (pKb)

-6.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

G423-0158 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G423-0158 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0158?
Check Price and Availability of G423-0158, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G423-0158 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0158
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0158
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0158 available by request