G423-0360 Screening compound: 4-[7-(3,4-difluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide

G423-0360 Screening compound: 4-[7-(3,4-difluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide
G423-0360 Screening compound: 4-[7-(3,4-difluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G423-0360
4-[7-(3,4-difluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G423-0360

Molecular Formula

C23H21F2N5O2 (C23 H21 F2 N5 O2)

Compound Name

4-[7-(3,4-difluorophenyl)-8-oxo-7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide

IUPAC name

4-[7-(34-difluorophenyl)-8-oxo-7H8H-[124]triazolo[43-a]pyrazin-3-yl]-N-(2-phenylethyl)butanamide

SMILES

O=C(CCCc1nnc2n1C=CN(c(cc1)cc(F)c1F)C2=O)NCCc1ccccc1

InChI

InChI=1S/C23H21F2N5O2/c24-18-10-9-17(15-19(18)25)29-13-14-30-20(27-28-22(30)23(29)32)7-4-8-21(31)26-12-11-16-5-2-1-3-6-16/h1-3,5-6,9-10,13-15H,4,7-8,11-12H2,(H,26,31)

InChI Key

FRUOHCBMUKSYSC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140556

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.45

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.067

Distribution Coefficient, logD

1.067

Water Solubility, LogSw

-1.82

Polar Surface Area

63.409

Acid Dissociation Constant (pKa)

14.38

Base Dissociation Constant (pKb)

-0.24

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

G423-0360 in Drug Discovery

Included in Screening Libraries

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G423-0360 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G423-0360?
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What is the minimum amount of G423-0360 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G423-0360
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G423-0360
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G423-0360 available by request