G427-1733 Screening compound: 3-[6-ethoxy-3,4-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide

G427-1733 Screening compound: 3-[6-ethoxy-3,4-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide
G427-1733 Screening compound: 3-[6-ethoxy-3,4-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-1733
3-[6-ethoxy-3,4-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-1733

Molecular Formula

C30H33N5O2 (C30 H33 N5 O2)

Compound Name

3-[6-ethoxy-3,4-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide

IUPAC name

3-[6-ethoxy-34-dimethyl-1-(3-methylphenyl)-1H-pyrazolo[34-b]pyridin-5-yl]-N-[2-(1H-indol-3-yl)ethyl]propanamide

SMILES

CCOc1c(CCC(NCCc2c[nH]c3c2cccc3)=O)c(C)c(c(C)nn2-c3cc(C)ccc3)c2n1

InChI

InChI=1S/C30H33N5O2/c1-5-37-30-24(13-14-27(36)31-16-15-22-18-32-26-12-7-6-11-25(22)26)20(3)28-21(4)34-35(29(28)33-30)23-10-8-9-19(2)17-23/h6-12,17-18,32H,5,13-16H2,1-4H3,(H,31,36)

InChI Key

SWFQXWGMXXJLLQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140812

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.62

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.537

Distribution Coefficient, logD

5.537

Water Solubility, LogSw

-6.03

Polar Surface Area

65.427

Acid Dissociation Constant (pKa)

14.04

Base Dissociation Constant (pKb)

1.90

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

G427-1733 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G427-1733 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-1733?
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What is the minimum amount of G427-1733 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-1733
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-1733
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-1733 available by request