G427-1830 Screening compound: methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamido}benzoate

G427-1830 Screening compound: methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamido}benzoate
G427-1830 Screening compound: methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamido}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-1830
methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamido}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-1830

Molecular Formula

C27H27FN4O4 (C27 H27 FN4 O4)

Compound Name

methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-3,4-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamido}benzoate

IUPAC name

methyl 4-{3-[6-ethoxy-1-(3-fluorophenyl)-34-dimethyl-1H-pyrazolo[34-b]pyridin-5-yl]propanamido}benzoate

SMILES

CCOc1c(CCC(Nc(cc2)ccc2C(OC)=O)=O)c(C)c(c(C)nn2-c3cccc(F)c3)c2n1

InChI

InChI=1S/C27H27FN4O4/c1-5-36-26-22(13-14-23(33)29-20-11-9-18(10-12-20)27(34)35-4)16(2)24-17(3)31-32(25(24)30-26)21-8-6-7-19(28)15-21/h6-12,15H,5,13-14H2,1-4H3,(H,29,33)

InChI Key

IAIUVDFWMYYHMP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140885

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.53

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.379

Distribution Coefficient, logD

5.378

Water Solubility, LogSw

-5.60

Polar Surface Area

75.567

Acid Dissociation Constant (pKa)

10.56

Base Dissociation Constant (pKb)

0.63

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

G427-1830 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with G427-1830 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-1830?
Check Price and Availability of G427-1830, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G427-1830 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-1830
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-1830
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-1830 available by request