G427-1832 Screening compound: 3-[6-ETHOXY-1-(3-FLUOROPHENYL)-3,4-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL]-N-[(PYRIDIN-3-YL)METHYL]PROPANAMIDE

G427-1832 Screening compound: 3-[6-ETHOXY-1-(3-FLUOROPHENYL)-3,4-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL]-N-[(PYRIDIN-3-YL)METHYL]PROPANAMIDE
G427-1832 Screening compound: 3-[6-ETHOXY-1-(3-FLUOROPHENYL)-3,4-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL]-N-[(PYRIDIN-3-YL)METHYL]PROPANAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-1832
3-[6-ETHOXY-1-(3-FLUOROPHENYL)-3,4-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL]-N-[(PYRIDIN-3-YL)METHYL]PROPANAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-1832

Molecular Formula

C25H26FN5O2 (C25 H26 FN5 O2)

Compound Name

3-[6-ETHOXY-1-(3-FLUOROPHENYL)-3,4-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-5-YL]-N-[(PYRIDIN-3-YL)METHYL]PROPANAMIDE

IUPAC name

n/a

SMILES

CCOc1c(CCC(NCc2cnccc2)=O)c(C)c(c(C)nn2-c3cccc(F)c3)c2n1

InChI

InChI=1S/C25H26FN5O2/c1-4-33-25-21(10-11-22(32)28-15-18-7-6-12-27-14-18)16(2)23-17(3)30-31(24(23)29-25)20-9-5-8-19(26)13-20/h5-9,12-14H,4,10-11,15H2,1-3H3,(H,28,32)

InChI Key

TZTSXRIESHFYCV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140886

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.51

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.760

Distribution Coefficient, logD

3.758

Water Solubility, LogSw

-3.98

Polar Surface Area

65.233

Acid Dissociation Constant (pKa)

13.53

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

G427-1832 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G427-1832 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-1832?
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What is the minimum amount of G427-1832 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-1832
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-1832
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-1832 available by request