G427-2172 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one

G427-2172 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one
G427-2172 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-2172
3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-2172

Molecular Formula

C22H26N4O2 (C22 H26 N4 O2)

Compound Name

3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one

IUPAC name

3-{6-methoxy-34-dimethyl-1-phenyl-1H-pyrazolo[34-b]pyridin-5-yl}-1-(pyrrolidin-1-yl)propan-1-one

SMILES

Cc(c(c1n2)c(C)c(CCC(N3CCCC3)=O)c2OC)nn1-c1ccccc1

InChI

InChI=1S/C22H26N4O2/c1-15-18(11-12-19(27)25-13-7-8-14-25)22(28-3)23-21-20(15)16(2)24-26(21)17-9-5-4-6-10-17/h4-6,9-10H,7-8,11-14H2,1-3H3

InChI Key

JWYXIIZOWVTSMQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27140981

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.47

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.741

Distribution Coefficient, logD

3.741

Water Solubility, LogSw

-4.30

Polar Surface Area

48.422

Acid Dissociation Constant (pKa)

21.00

Base Dissociation Constant (pKb)

0.84

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

G427-2172 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G427-2172 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-2172?
Check Price and Availability of G427-2172, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G427-2172 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-2172
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-2172
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-2172 available by request