G427-2181 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide

G427-2181 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide
G427-2181 Screening compound: 3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-2181
3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-2181

Molecular Formula

C23H28N4O3 (C23 H28 N4 O3)

Compound Name

3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide

IUPAC name

3-{6-methoxy-34-dimethyl-1-phenyl-1H-pyrazolo[34-b]pyridin-5-yl}-N-[(oxolan-2-yl)methyl]propanamide

SMILES

Cc(c(c1n2)c(C)c(CCC(NCC3OCCC3)=O)c2OC)nn1-c1ccccc1

InChI

InChI=1S/C23H28N4O3/c1-15-19(11-12-20(28)24-14-18-10-7-13-30-18)23(29-3)25-22-21(15)16(2)26-27(22)17-8-5-4-6-9-17/h4-6,8-9,18H,7,10-14H2,1-3H3,(H,24,28)/t18-/m1/s1

InChI Key

DJGBVEHRVLKUFC-GOSISDBHSA-N

MDL Number (MFCD)

MFCD27140986

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.823

Distribution Coefficient, logD

2.823

Water Solubility, LogSw

-3.51

Polar Surface Area

64.790

Acid Dissociation Constant (pKa)

13.92

Base Dissociation Constant (pKb)

0.84

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

G427-2181 in Drug Discovery

Included in Screening Libraries

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with G427-2181 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-2181?
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What is the minimum amount of G427-2181 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-2181
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-2181
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-2181 available by request