G427-2210 Screening compound: N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}propanamide

G427-2210 Screening compound: N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}propanamide
G427-2210 Screening compound: N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G427-2210
N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G427-2210

Molecular Formula

C30H35N5O2 (C30 H35 N5 O2)

Compound Name

N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-3,4-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-yl}propanamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-3-{6-methoxy-34-dimethyl-1-phenyl-1H-pyrazolo[34-b]pyridin-5-yl}propanamide

SMILES

Cc(c(c1n2)c(C)c(CCC(NC3CCN(Cc4ccccc4)CC3)=O)c2OC)nn1-c1ccccc1

InChI

InChI=1S/C30H35N5O2/c1-21-26(30(37-3)32-29-28(21)22(2)33-35(29)25-12-8-5-9-13-25)14-15-27(36)31-24-16-18-34(19-17-24)20-23-10-6-4-7-11-23/h4-13,24H,14-20H2,1-3H3,(H,31,36)

InChI Key

HLMKCQBINNNVJA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27141012

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.64

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.616

Distribution Coefficient, logD

3.058

Water Solubility, LogSw

-4.57

Polar Surface Area

59.401

Acid Dissociation Constant (pKa)

15.87

Base Dissociation Constant (pKb)

8.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.70

G427-2210 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with G427-2210 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G427-2210?
Check Price and Availability of G427-2210, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G427-2210 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G427-2210
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G427-2210
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G427-2210 available by request