G430-2901 Screening compound: N-[(3-chlorophenyl)methyl]-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carboxamide

G430-2901 Screening compound: N-[(3-chlorophenyl)methyl]-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carboxamide
G430-2901 Screening compound: N-[(3-chlorophenyl)methyl]-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G430-2901
N-[(3-chlorophenyl)methyl]-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G430-2901

Molecular Formula

C27H28ClN5O (C27 H28 ClN5 O)

Compound Name

N-[(3-chlorophenyl)methyl]-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-3-carboxamide

IUPAC name

N-[(3-chlorophenyl)methyl]-1-[2-(24-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-3-carboxamide

SMILES

Cc(cc1)cc(C)c1-c1nn(ccnc2N(CCC3)CC3C(NCc3cccc(Cl)c3)=O)c2c1

InChI

InChI=1S/C27H28ClN5O/c1-18-8-9-23(19(2)13-18)24-15-25-26(29-10-12-33(25)31-24)32-11-4-6-21(17-32)27(34)30-16-20-5-3-7-22(28)14-20/h3,5,7-10,12-15,21H,4,6,11,16-17H2,1-2H3,(H,30,34)/t21-/m0/s1

InChI Key

PVBWYHSPWJNYSP-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27141247

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.01

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.983

Distribution Coefficient, logD

4.980

Water Solubility, LogSw

-4.91

Polar Surface Area

47.621

Acid Dissociation Constant (pKa)

12.36

Base Dissociation Constant (pKb)

5.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.60

G430-2901 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with G430-2901 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G430-2901?
Check Price and Availability of G430-2901, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G430-2901 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G430-2901
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G430-2901
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G430-2901 available by request