G431-0018 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

G431-0018 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
G431-0018 Screening compound: N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound G431-0018
N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G431-0018

Molecular Formula

C17H14FN5O (C17 H14 FN5 O)

Compound Name

N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

IUPAC name

N-(3-fluoro-4-methylphenyl)-2-(furan-2-yl)-5-methyl-[124]triazolo[15-a]pyrimidin-7-amine

SMILES

Cc(ccc(Nc1cc(C)nc2nc(-c3ccco3)nn12)c1)c1F

InChI

InChI=1S/C17H14FN5O/c1-10-5-6-12(9-13(10)18)20-15-8-11(2)19-17-21-16(22-23(15)17)14-4-3-7-24-14/h3-9,20H,1-2H3

InChI Key

MNGNDNJHOYEFMA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15013653

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.735

Distribution Coefficient, logD

3.730

Water Solubility, LogSw

-3.90

Polar Surface Area

48.419

Acid Dissociation Constant (pKa)

15.25

Base Dissociation Constant (pKb)

5.42

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

G431-0018 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with G431-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G431-0018?
Check Price and Availability of G431-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G431-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G431-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G431-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G431-0018 available by request