G433-0628 Screening compound: 3-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea

G433-0628 Screening compound: 3-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea
G433-0628 Screening compound: 3-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound G433-0628
3-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G433-0628

Molecular Formula

C23H21FN4O3 (C23 H21 FN4 O3)

Compound Name

3-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea

IUPAC name

3-(13-dimethyl-2-oxo-6-phenoxy-23-dihydro-1H-13-benzodiazol-5-yl)-1-[(3-fluorophenyl)methyl]urea

SMILES

CN(c(c(N1C)c2)cc(NC(NCc3cccc(F)c3)=O)c2Oc2ccccc2)C1=O

InChI

InChI=1S/C23H21FN4O3/c1-27-19-12-18(26-22(29)25-14-15-7-6-8-16(24)11-15)21(13-20(19)28(2)23(27)30)31-17-9-4-3-5-10-17/h3-13H,14H2,1-2H3,(H2,25,26,29)

InChI Key

AWZDHSUCHRSSLA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27141457

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.076

Distribution Coefficient, logD

4.076

Water Solubility, LogSw

-4.27

Polar Surface Area

57.685

Acid Dissociation Constant (pKa)

13.08

Base Dissociation Constant (pKb)

0.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G433-0628 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G433-0628 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G433-0628?
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What is the minimum amount of G433-0628 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G433-0628
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G433-0628
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G433-0628 available by request