G433-0858 Screening compound: methyl 2-[(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoate

G433-0858 Screening compound: methyl 2-[(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoate
G433-0858 Screening compound: methyl 2-[(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G433-0858
methyl 2-[(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G433-0858

Molecular Formula

C23H21N3O6S (C23 H21 N3 O6 S)

Compound Name

methyl 2-[(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)sulfamoyl]benzoate

IUPAC name

methyl 2-[(13-dimethyl-2-oxo-6-phenoxy-23-dihydro-1H-13-benzodiazol-5-yl)sulfamoyl]benzoate

SMILES

CN(c(c(N1C)c2)cc(NS(c(cccc3)c3C(OC)=O)(=O)=O)c2Oc2ccccc2)C1=O

InChI

InChI=1S/C23H21N3O6S/c1-25-18-13-17(24-33(29,30)21-12-8-7-11-16(21)22(27)31-3)20(14-19(18)26(2)23(25)28)32-15-9-5-4-6-10-15/h4-14,24H,1-3H3

InChI Key

JDCFAZJNROYMPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27141547

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.812

Distribution Coefficient, logD

3.713

Water Solubility, LogSw

-4.07

Polar Surface Area

85.883

Acid Dissociation Constant (pKa)

7.99

Base Dissociation Constant (pKb)

-2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

G433-0858 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with G433-0858 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G433-0858?
Check Price and Availability of G433-0858, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G433-0858 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G433-0858
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G433-0858
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G433-0858 available by request