G433-1012 Screening compound: 4-cyano-N-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide

G433-1012 Screening compound: 4-cyano-N-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide
G433-1012 Screening compound: 4-cyano-N-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G433-1012
4-cyano-N-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G433-1012

Molecular Formula

C22H18N4O4S (C22 H18 N4 O4 S)

Compound Name

4-cyano-N-(1,3-dimethyl-2-oxo-6-phenoxy-2,3-dihydro-1H-1,3-benzodiazol-5-yl)benzene-1-sulfonamide

IUPAC name

4-cyano-N-(13-dimethyl-2-oxo-6-phenoxy-23-dihydro-1H-13-benzodiazol-5-yl)benzene-1-sulfonamide

SMILES

CN(c(c(N1C)c2)cc(NS(c(cc3)ccc3C#N)(=O)=O)c2Oc2ccccc2)C1=O

InChI

InChI=1S/C22H18N4O4S/c1-25-19-12-18(24-31(28,29)17-10-8-15(14-23)9-11-17)21(13-20(19)26(2)22(25)27)30-16-6-4-3-5-7-16/h3-13,24H,1-2H3

InChI Key

BUUWWBBOMXNGKA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27141614

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.48

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.782

Distribution Coefficient, logD

3.646

Water Solubility, LogSw

-4.14

Polar Surface Area

81.765

Acid Dissociation Constant (pKa)

7.83

Base Dissociation Constant (pKb)

-2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

G433-1012 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Anti-Inflammatory Library (24602 compounds)

Antimitotic Tubulin Library (17355 compounds)

Antiviral Library (67538 compounds)

Hsp90-Targeted Library (11355 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G433-1012 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G433-1012?
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What is the minimum amount of G433-1012 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G433-1012
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G433-1012
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G433-1012 available by request