G434-0065 Screening compound: N-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

G434-0065 Screening compound: N-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide
G434-0065 Screening compound: N-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G434-0065
N-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G434-0065

Molecular Formula

C18H17N3O5S (C18 H17 N3 O5 S)

Compound Name

N-(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

IUPAC name

N-(3-methyl-2-oxo-23-dihydro-13-benzoxazol-6-yl)-4-(2-oxopyrrolidin-1-yl)benzene-1-sulfonamide

SMILES

CN(c(ccc(NS(c(cc1)ccc1N(CCC1)C1=O)(=O)=O)c1)c1O1)C1=O

InChI

InChI=1S/C18H17N3O5S/c1-20-15-9-4-12(11-16(15)26-18(20)23)19-27(24,25)14-7-5-13(6-8-14)21-10-2-3-17(21)22/h4-9,11,19H,2-3,10H2,1H3

InChI Key

PFLCZWBACIBCJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11691953

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.42

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.982

Distribution Coefficient, logD

1.905

Water Solubility, LogSw

-3.03

Polar Surface Area

80.570

Acid Dissociation Constant (pKa)

8.11

Base Dissociation Constant (pKb)

-0.14

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

G434-0065 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with G434-0065 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G434-0065?
Check Price and Availability of G434-0065, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G434-0065 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G434-0065
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G434-0065
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G434-0065 available by request