G434-0183 Screening compound: ethyl 4-{[(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)carbamoyl]amino}benzoate

G434-0183 Screening compound: ethyl 4-{[(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)carbamoyl]amino}benzoate
G434-0183 Screening compound: ethyl 4-{[(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)carbamoyl]amino}benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound G434-0183
ethyl 4-{[(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)carbamoyl]amino}benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G434-0183

Molecular Formula

C18H17N3O5 (C18 H17 N3 O5)

Compound Name

ethyl 4-{[(3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)carbamoyl]amino}benzoate

IUPAC name

ethyl 4-{[(3-methyl-2-oxo-23-dihydro-13-benzoxazol-6-yl)carbamoyl]amino}benzoate

SMILES

CCOC(c(cc1)ccc1NC(Nc(cc1)cc(O2)c1N(C)C2=O)=O)=O

InChI

InChI=1S/C18H17N3O5/c1-3-25-16(22)11-4-6-12(7-5-11)19-17(23)20-13-8-9-14-15(10-13)26-18(24)21(14)2/h4-10H,3H2,1-2H3,(H2,19,20,23)

InChI Key

GANGKZOPRKABIH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27141672

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

355.35

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.535

Distribution Coefficient, logD

3.535

Water Solubility, LogSw

-3.96

Polar Surface Area

76.161

Acid Dissociation Constant (pKa)

12.06

Base Dissociation Constant (pKb)

-0.94

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

G434-0183 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with G434-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G434-0183?
Check Price and Availability of G434-0183, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G434-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G434-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G434-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G434-0183 available by request