G435-0001 Screening compound: N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[1,5-a]pyrazin-4-yl}piperidine-4-carboxamide

G435-0001 Screening compound: N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[1,5-a]pyrazin-4-yl}piperidine-4-carboxamide
G435-0001 Screening compound: N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[1,5-a]pyrazin-4-yl}piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0001
N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[1,5-a]pyrazin-4-yl}piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0001

Molecular Formula

C25H24ClN5O (C25 H24 ClN5 O)

Compound Name

N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[1,5-a]pyrazin-4-yl}piperidine-4-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-1-{2-phenylpyrazolo[15-a]pyrazin-4-yl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(c1c2)nccn1nc2-c1ccccc1)NCc(cc1)ccc1Cl

InChI

InChI=1S/C25H24ClN5O/c26-21-8-6-18(7-9-21)17-28-25(32)20-10-13-30(14-11-20)24-23-16-22(19-4-2-1-3-5-19)29-31(23)15-12-27-24/h1-9,12,15-16,20H,10-11,13-14,17H2,(H,28,32)

InChI Key

YJWPUDBBKVDDGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.95

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.236

Distribution Coefficient, logD

4.234

Water Solubility, LogSw

-4.63

Polar Surface Area

47.688

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G435-0001 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

PLpro Library (6343 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with G435-0001 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0001?
Check Price and Availability of G435-0001, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-0001 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0001
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0001
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0001 available by request