G435-0119 Screening compound: N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

G435-0119 Screening compound: N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide
G435-0119 Screening compound: N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0119
N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0119

Molecular Formula

C25H23ClFN5O (C25 H23 ClFN5 O)

Compound Name

N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

IUPAC name

N-[(4-chlorophenyl)methyl]-1-[2-(4-fluorophenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(c1c2)nccn1nc2-c(cc1)ccc1F)NCc(cc1)ccc1Cl

InChI

InChI=1S/C25H23ClFN5O/c26-20-5-1-17(2-6-20)16-29-25(33)19-9-12-31(13-10-19)24-23-15-22(30-32(23)14-11-28-24)18-3-7-21(27)8-4-18/h1-8,11,14-15,19H,9-10,12-13,16H2,(H,29,33)

InChI Key

PNPNDHJXQAUHDX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142094

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

463.94

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.370

Distribution Coefficient, logD

4.368

Water Solubility, LogSw

-4.61

Polar Surface Area

47.688

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

G435-0119 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G435-0119 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0119?
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What is the minimum amount of G435-0119 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0119
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0119
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0119 available by request