G435-0183 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide

G435-0183 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide
G435-0183 Screening compound: 1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0183
1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0183

Molecular Formula

C27H28FN5O (C27 H28 FN5 O)

Compound Name

1-[2-(3,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide

IUPAC name

1-[2-(34-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide

SMILES

Cc(cc1)c(C)cc1-c1nn(ccnc2N(CC3)CCC3C(NCc(cc3)ccc3F)=O)c2c1

InChI

InChI=1S/C27H28FN5O/c1-18-3-6-22(15-19(18)2)24-16-25-26(29-11-14-33(25)31-24)32-12-9-21(10-13-32)27(34)30-17-20-4-7-23(28)8-5-20/h3-8,11,14-16,21H,9-10,12-13,17H2,1-2H3,(H,30,34)

InChI Key

AJLXOXLNPIUHKB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142123

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.637

Distribution Coefficient, logD

4.634

Water Solubility, LogSw

-4.35

Polar Surface Area

47.688

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

5.23

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

G435-0183 in Drug Discovery

Included in Screening Libraries

CORONAVIRUS Library (20774 compounds)

PLpro Library (6343 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G435-0183 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0183?
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What is the minimum amount of G435-0183 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0183
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0183
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0183 available by request