G435-0243 Screening compound: N-butyl-1-[2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

G435-0243 Screening compound: N-butyl-1-[2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide
G435-0243 Screening compound: N-butyl-1-[2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0243
N-butyl-1-[2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0243

Molecular Formula

C20H25N5OS (C20 H25 N5 OS)

Compound Name

N-butyl-1-[2-(thiophen-2-yl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

IUPAC name

N-butyl-1-[2-(thiophen-2-yl)pyrazolo[15-a]pyrazin-4-yl]piperidine-4-carboxamide

SMILES

CCCCNC(C(CC1)CCN1c(c1c2)nccn1nc2-c1cccs1)=O

InChI

InChI=1S/C20H25N5OS/c1-2-3-8-22-20(26)15-6-10-24(11-7-15)19-17-14-16(18-5-4-13-27-18)23-25(17)12-9-21-19/h4-5,9,12-15H,2-3,6-8,10-11H2,1H3,(H,22,26)

InChI Key

RIRUJYZPVWUNBP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142135

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.463

Distribution Coefficient, logD

3.461

Water Solubility, LogSw

-3.59

Polar Surface Area

48.819

Acid Dissociation Constant (pKa)

14.41

Base Dissociation Constant (pKb)

4.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

45.00

G435-0243 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with G435-0243 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0243?
Check Price and Availability of G435-0243, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-0243 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0243
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0243
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0243 available by request