G435-0572 Screening compound: N-cyclohexyl-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

G435-0572 Screening compound: N-cyclohexyl-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide
G435-0572 Screening compound: N-cyclohexyl-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0572
N-cyclohexyl-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0572

Molecular Formula

C26H33N5O (C26 H33 N5 O)

Compound Name

N-cyclohexyl-1-[2-(2,4-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]piperidine-4-carboxamide

IUPAC name

N-cyclohexyl-1-[2-(24-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]piperidine-4-carboxamide

SMILES

Cc(cc1)cc(C)c1-c1nn(ccnc2N(CC3)CCC3C(NC3CCCCC3)=O)c2c1

InChI

InChI=1S/C26H33N5O/c1-18-8-9-22(19(2)16-18)23-17-24-25(27-12-15-31(24)29-23)30-13-10-20(11-14-30)26(32)28-21-6-4-3-5-7-21/h8-9,12,15-17,20-21H,3-7,10-11,13-14H2,1-2H3,(H,28,32)

InChI Key

VMBSVLAOKDTDKL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142164

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

431.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.891

Distribution Coefficient, logD

4.889

Water Solubility, LogSw

-4.51

Polar Surface Area

47.413

Acid Dissociation Constant (pKa)

15.04

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

G435-0572 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with G435-0572 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0572?
Check Price and Availability of G435-0572, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of G435-0572 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0572
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0572
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0572 available by request