G435-0653 Screening compound: 1-[2-(2,5-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide

G435-0653 Screening compound: 1-[2-(2,5-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide
G435-0653 Screening compound: 1-[2-(2,5-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound G435-0653
1-[2-(2,5-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

G435-0653

Molecular Formula

C27H29N5O (C27 H29 N5 O)

Compound Name

1-[2-(2,5-dimethylphenyl)pyrazolo[1,5-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide

IUPAC name

1-[2-(25-dimethylphenyl)pyrazolo[15-a]pyrazin-4-yl]-N-(4-methylphenyl)piperidine-4-carboxamide

SMILES

Cc(cc1)ccc1NC(C(CC1)CCN1c(c1c2)nccn1nc2-c1c(C)ccc(C)c1)=O

InChI

InChI=1S/C27H29N5O/c1-18-5-8-22(9-6-18)29-27(33)21-10-13-31(14-11-21)26-25-17-24(30-32(25)15-12-28-26)23-16-19(2)4-7-20(23)3/h4-9,12,15-17,21H,10-11,13-14H2,1-3H3,(H,29,33)

InChI Key

BOKYRNDVLZBANA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27142177

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.56

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.082

Distribution Coefficient, logD

5.080

Water Solubility, LogSw

-4.74

Polar Surface Area

46.366

Acid Dissociation Constant (pKa)

11.95

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

G435-0653 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with G435-0653 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound G435-0653?
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What is the minimum amount of G435-0653 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for G435-0653
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for G435-0653
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of G435-0653 available by request